Direct (nonstop) flights from Santa Cruz to Panama City
2 airlines fly nonstop from Santa Cruz (VVI) to Tocumen International (PTY). It's 2,145 miles (3,452 km), about 4h 50m in the air. Operated by Copa Airlines, Boliviana de Aviación.
Copa Airlines
Boliviana de Aviación
Route data last updated: May 27, 2026
Airlines with non-stop flights
OB
Boliviana de Aviación
Alternative Routes
Other ways to fly from Santa Cruz to Panama City with one stop · direct emits 362 kg CO₂ per passenger
Looking for the return flight?
PTY → VVI: Flights from Panama City to Santa CruzOther direct flights from Santa Cruz
Direct flights from Panama City (PTY)
Frequently Asked Questions
How long is the direct flight from Santa Cruz to Panama City?
A nonstop flight from Santa Cruz (VVI) to Panama City (PTY) takes approximately 4 hours and 50 minutes. The distance is 2,145 miles (3,452 km).
Which airlines fly nonstop from Santa Cruz to Panama City?
2 airlines: Copa Airlines, Boliviana de Aviación.
Is there a nonstop flight from Santa Cruz to Panama City?
Yes. 2 airlines: Copa Airlines, Boliviana de Aviación.
How far is Santa Cruz from Panama City?
The flight distance from Santa Cruz to Panama City is 2,145 miles (3,452 km), measured as the great-circle (shortest air) distance. That's roughly the same distance as New York to Los Angeles.
What is the time difference between Santa Cruz and Panama City?
Panama City is 1 hour behind Santa Cruz. (America/La_Paz vs America/Panama.)
What type of aircraft flies from Santa Cruz to Panama City?
At 4h 50m, this route typically uses narrow-body or mid-range jets — Boeing 737 MAX or Airbus A320neo. Varies by airline.
Do I need a visa to travel from Bolivia to Panama?
Depends on your passport. Check with the Panama embassy or an official visa portal before booking — requirements change.
What is the carbon footprint of a flight from Santa Cruz to Panama City?
Roughly 362 kg CO2 per passenger one-way. That's about the same as driving 1,810 km.
Is the return flight from Panama City to Santa Cruz also nonstop?
Yes — nonstop flights run both ways. Flight time may differ slightly due to wind patterns.
When is the cheapest time to fly from Santa Cruz to Panama City?
Midweek flights (Tue/Wed) outside holiday peaks are usually cheapest. For long-haul, booking 2-3 months out tends to help. Use "Check Prices" above to compare.
How early should I arrive at Santa Cruz for this flight?
3 hours before departure for international flights. You need time for check-in, security, and immigration.